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Additional file 9: Figure S7. of Revised computational metagenomic processing uncovers hidden and biologically meaningful functional variation in the human microbiome

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posted on 08.02.2017, 05:00 by Ohad Manor, Elhanan Borenstein
Association of pathways to type 2 diabetes (T2D) with and without accounting for factors masking functional variability. Shown is a scatter plot of the differential abundance score (W-statistic of the Wilcoxon rank-sum test) of each pathway when comparing T2D cases and controls, using either the standard (x-axis) or revised (y-axis) metagenomic bioinformatic processing pipelines. Each point represents a single pathway and is additionally marked by its KEGG identifier. The dashed red lines represent the FDR<0.05 significance cutoff for each metagenomic processing pipeline. (PDF 251 kb)


National Institute of Diabetes and Digestive and Kidney Diseases