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Additional file 5 of Acute colitis during chronic experimental traumatic brain injury in mice induces dysautonomia and persistent extraintestinal, systemic, and CNS inflammation with exacerbated neurological deficits

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posted on 19.01.2021, 04:38 by Marie Hanscom, David J. Loane, Taryn Aubretch, Jenna Leser, Kara Molesworth, Nivedita Hedgekar, Rodney M. Ritzel, Gelareh Abulwerdi, Terez Shea-Donohue, Alan I. Faden
Additional file 5: Supplemental Figure 3. Object exploration times during NOR testing were unaltered by TBI or intestinal inflammation. Total time spent exploring objects during the familiarization stage and novel object stage conducted prior to DSS administration (A, D), during the DSS injury phase (B, E) and in the fourth week of the DSS recovery phase (C, F). Mice from all experimental groups spent similar amounts of time exploring the objects presented during each stage. Data represented as mean ± s.e.m (n = 31-42/group pre-DSS administration; n = 15-21/group DSS injury phase and fourth DSS recovery week).


National Institutes of Health Science Foundation Ireland National Institute of Diabetes and Digestive and Kidney Diseases Brain Injury Association of America