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Additional file 5: Figure S3. of Revised computational metagenomic processing uncovers hidden and biologically meaningful functional variation in the human microbiome

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posted on 08.02.2017, 05:00 by Ohad Manor, Elhanan Borenstein
Relative normalization impacts functional variation of pathways in simulated microbial communities. Shown is a scatter plot illustrating the CoV of each pathway calculated for 100 simulated metagenomic communities comprised of 100 reference genomes with varying abundances. The true CoV is shown on the x-axis, while the calculated CoV after relative normalization (red) or MUSiCC (blue) is shown on the y-axis. GG: Glycolysis/Gluconeogenesis; R: Ribosome. (PDF 251 kb)


National Institute of Diabetes and Digestive and Kidney Diseases