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Additional file 4: of Assessment of new HDAC inhibitors for immunotherapy of malignant pleural mesothelioma

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posted on 18.06.2018, 05:00 by Douae Bensaid, Thibaut Blondy, Sophie Deshayes, Virginie Dehame, Philippe Bertrand, Marc Grégoire, Mohammed Errami, Christophe Blanquart
Figure S1. Effect of HDAC inhibitors on naïve and memory T-cells. Lymphocytes obtained by elutriation were treated with HDACi at the following concentrations for 48 h: VPA 5 mM, SAHA 1 μM, ODB 32 μM, NODB 8 μM, ODH 4 μM, and NODH 50 nM. Graphics represent the effect of the compounds on CD4 (a) and CD8 (b) naïve T-cells and on CD4 (c) and CD8 (d) memory T-cells. Results are expressed as the means ± S.E.M of three independent experiments. (PDF 108 kb)

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