Additional file 1: of Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

Vachon, Celine; Scott, Christopher; Tamimi, Rulla; Thompson, Deborah; Fasching, Peter; Stone, Jennifer; Southey, Melissa; Winham, Stacey; LindstrĂśm, Sara; Lilyquist, Jenna; Giles, Graham; Milne, Roger; MacInnis, Robert; Baglietto, Laura; Li, Jingmei; Czene, Kamila; Bolla, Manjeet; Wang, Qin; Dennis, Joe; Haeberle, Lothar; Eriksson, Mikael; Kraft, Peter; Luben, Robert; Wareham, Nick; Olson, Janet; Norman, Aaron; Polley, Eric; Maskarinec, Gertraud; Marchand, Loic; Haiman, Christopher; Hopper, John; Couch, Fergus; Easton, Douglas; Hall, Per; Chatterjee, Nilanjan; Garcia-Closas, Montse

doi:10.6084/m9.figshare.8171870.v1

13058_2019_1138_MOESM1_ESM.docx (34.63 kB)

Additional file 1: of Joint association of mammographic density adjusted for age and body mass index and polygenic risk score with breast cancer risk

journal contribution

posted on 2019-05-22, 05:00 authored by Celine Vachon, Christopher Scott, Rulla Tamimi, Deborah Thompson, Peter Fasching, Jennifer Stone, Melissa Southey, Stacey Winham, Sara LindstrĂśm, Jenna Lilyquist, Graham Giles, Roger Milne, Robert MacInnis, Laura Baglietto, Jingmei Li, Kamila Czene, Manjeet Bolla, Qin Wang, Joe Dennis, Lothar Haeberle, Mikael Eriksson, Peter Kraft, Robert Luben, Nick Wareham, Janet Olson, Aaron Norman, Eric Polley, Gertraud Maskarinec, Loic Marchand, Christopher Haiman, John Hopper, Fergus Couch, Douglas Easton, Per Hall, Nilanjan Chatterjee, Montse Garcia-Closas

Table S1. Study design and characteristics for eight participating studies. Table S2. Characteristics of cases and non-cases by study (% of non-missing). Table S3. Associations (OR, 95% CI) of adjusted percent density (PD), adjusted dense area (DA) and polygenic risk score (PRS) with breast cancer by study. Adjusted for age and BMI. Table S4. Goodness of fit test P values for joint effect of adjusted* density measures with 77-SNP polygenic risk score (PRS) on breast cancer, based on six population-based studies. PRS and density measures are continuous (per 1 standard deviation, SD). (DOCX 34 kb)