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Additional file 1: of Initiation of LPS-induced pulmonary dysfunction and its recovery occur independent of T cells

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posted on 22.11.2018, 05:00 authored by Eva Verjans, Stephanie Kanzler, Kim Ohl, Annette Rieg, Nadine Ruske, Angela Schippers, Norbert Wagner, Klaus Tenbrock, Stefan Uhlig, Christian Martin
Figure S1. Bronchial hyperresponsiveness in C57BL6 mice in LPS-induced acute lung injury. Mice were instilled with 50 μL of LPS (4 mg/kg) or saline (controls) on day 0 and were mechanically ventilated 1, 4 or 10 days after ARDS induction. Mice of basal group were mechanical ventilated without prior i.t. instillation. (A-D) Lung function parameters resistance (Rrs), elastance (Ers), tissue damping (G) and tissue elastance (H) on day 1, 4 and 10 after ARDS-induction following acetylcholine stimulation (controls n = 4, ARDS group n = 6 per time point, means ± SEM). * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. (PDF 311 kb)


Grant of the german lung foundation