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Additional file 1: of Initiation of LPS-induced pulmonary dysfunction and its recovery occur independent of T cells

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posted on 22.11.2018, 05:00 by Eva Verjans, Stephanie Kanzler, Kim Ohl, Annette Rieg, Nadine Ruske, Angela Schippers, Norbert Wagner, Klaus Tenbrock, Stefan Uhlig, Christian Martin
Figure S1. Bronchial hyperresponsiveness in C57BL6 mice in LPS-induced acute lung injury. Mice were instilled with 50 μL of LPS (4 mg/kg) or saline (controls) on day 0 and were mechanically ventilated 1, 4 or 10 days after ARDS induction. Mice of basal group were mechanical ventilated without prior i.t. instillation. (A-D) Lung function parameters resistance (Rrs), elastance (Ers), tissue damping (G) and tissue elastance (H) on day 1, 4 and 10 after ARDS-induction following acetylcholine stimulation (controls n = 4, ARDS group n = 6 per time point, means ± SEM). * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. (PDF 311 kb)


Grant of the german lung foundation