Additional file 1 of Heat-killed Lacticaseibacillus paracasei GMNL-653 ameliorates human scalp health by regulating scalp microbiome

Additional file 1: Table S1. The primer sequences of hair follicle growth factor-related genes (A) and hair follicle microbiota-related genes (B). Table S2. Correlations of the fungus or the bacteria with scalp conditions in the shampoo clinical trial. Figure S1. Heat-killed L. paracasei GMNL-653 modulates microbiota diversity in the subgroups of normal dandruff (A), high dandruff (B), normal oil (C), high oil (D), normal hair (E), and less hair (F). Start group (Start) described as the scalp in the beginning without any shampoo treatment. Control group (Ctrl) represented as the use of control shampoo without adding heat-killed GMNL-653 for 1 month. GMNL-653 group (GMNL-653) meant the use of heat-killed GMNL-653 shampoo for 1 month after using Ctrl shampoo. * p < 0.05 compared with Start group. # p < 0.05 compared with the Ctrl group. Figure S2. Hair volume is positive-correlated with accumulation of L. paracasei in human scalp after using heat-killed GMNL-653 shampoo for 2 months (A) and 4 months (B). Pearson correlation coefficient (R) and p value were calculated by SPSS statistics.