Additional file 1 of Dual mode imaging guided multi-functional bio-targeted oxygen production probes for tumor therapy

Additional file 1: Fig. S1. Light microscope image of ICP-CLs@O2 (400 magnification). Fig. S2. The standard curve of IR780. Fig. S3. The standard curve of CBP. Fig. S4. In vitro release curves of CBP. Fig. S5. Particle size of ICP-CLs@O2 over a period of 13 days. Fig. S6. Zeta potential of ICP-CLs@O2 over a period of 13 days Fig. S7. The hemolysis test of ICP-CLs@O2 at different concentrations. Fig. S8. Flow cytometry analysis binding between Bifidobacterium longum and DiI-labeled ICP-CLs@O2. Fig. S9. Cell viability assay of different concentration ICP-CLs@O2 incubated with HUVECs. Fig. S10. Variation trend of body weight in different groups of mice. Fig. S11. Hematological assay of BALB/c mice. Fig. S12. H&E staining of major organs from the control group and the treated groups.