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Additional file 1: Figure S1. of Investigation on changes of modularity and robustness by edge-removal mutations in signaling networks

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posted on 21.12.2017, 05:00 by Cong-Doan Truong, Yung-Keun Kwon
Analysis of the changes of the modularity and the robustness by edge-removal mutations in STF signaling network. Figure S2. Analysis of the changes of the modularity and the robustness by edge-removal mutations in HIV-1 signaling network. Figure S3. Analysis of normal distributions of averages of modularity changes and robustness changes in T-LGL network. Figure S4. Analysis of normal distributions of averages of modularity changes and robustness changes in STF network. Figure S5. Analysis of normal distributions of averages of modularity changes and robustness changes in HIV-1 network. Figure S6. Analysis of outliers of averages of modularity changes and robustness changes in T-LGL network. Figure S7. Analysis of outliers of averages of modularity changes and robustness changes in STF network. Figure S8. Analysis of outliers of averages of modularity changes and robustness changes in HIV-1 network. Figure S9. Relationship between the changes of the modularity and the robustness in T-LGL signaling network. Figure S10. Relationship between the changes of the modularity and the robustness in random networks. Figure S11. Relationship of each of the changes of the modularity and the robustness with the structural properties in STF signaling network. Figure S12. Relationship of each of the changes of the modularity and the robustness with the structural properties in HIV-1 signaling network. Figure S13. Relationship of each of the changes of the modularity and the robustness with the structural properties in random networks shuffled from T-LGL network. Figure S14. Relationship of each of the changes of the modularity and the robustness with the structural properties in random networks shuffled from STF network. Figure S15. Relationship of each of the changes of the modularity and the robustness with the structural properties in random networks shuffled from HIV-1 network. Figure S16. Topological distributions of High-MI/High-RD edges and their incident nodes in STF signaling network. Figure S17. Topological distributions of High-MI/High-RD edges and their incident nodes in HIV-1 signaling network. Figure S18. Edge-removal analysis for edgetic drug discovery in STF signaling network. Figure S19. Edge-removal analysis for edgetic drug discovery in HIV-1 signaling network. Table S1. GO analysis results between High-MI-incident/High-RD-incident group and the rest of genes in STF network. Table S2. GO analysis results between High-MI-incident/High-RD-incident group and the rest of genes in HIV-1 network. (PDF 3490 kb)

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