A practical and facile approach towards indole alkaloids: (-)-mitralactonine
Version 2 2024-03-12, 21:25Version 2 2024-03-12, 21:25
Version 1 2023-10-19, 21:06Version 1 2023-10-19, 21:06
journal contribution
posted on 2024-03-12, 21:25authored bySubhash P. Chavan, Pallavi Sharma, Rasapalli Sivappa, Uttam R. Kalkote
An efficient approach to (-)-mitralactonine using Pictet-Spengler cyclisation with a highly functionalised masked aldehyde is described. Sharpless asymmetric dihydroxylation (SAD) is utilised to introduce chirality in the key substrate.