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A new phenol derivative isolated from mangrove-derived fungus Eupenicillium sp. HJ002

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journal contribution
posted on 2020-01-21, 13:15 authored by Rong-Qing Mei, Xu-Hua Nong, Bin Wang, Xue-Ping Sun, Guo-Lei Huang, You-Ping Luo, Cai-Juan Zheng, Guang-Ying Chen

A new phenol derivative, 3-chloro-5-hydroxy-4-methoxyphenylacetic acid methyl ester (1), along with five known compounds methyl 4-hydroxyphenylacetate (2), cytosporone B (3), (R)-striatisporolide A (4), (R)-butanedioic acid (5) and ergosterol (6) were isolated from the mangrove-derived fungus Eupenicillium sp. HJ002. Their structures were established by spectroscopic methods, GIAO based 13C NMR chemical shift calculations and comparison with the data of literature. Compounds 1–5 were isolated from Xylocarpus granatum Koening-derived fungus for the first time.

Funding

This work was supported by the National Natural Science Foundation of Hainan Province (No. 218MS045), Key Research and Development Program of Hainan Province (No. ZDYF2018183), Error! Hyperlink reference not valid. (No. 2016GXNSFBA380011), the National Natural Science Foundation of China (Nos. 31760093, 21462015 and 21662012) and Innovation Project of Postgraduate (No. Hys2018-213).

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