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A Simple Catalytic Method for the Regioselective Halogenation of Arenes

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journal contribution
posted on 2006-06-08, 00:00 authored by Dipannita Kalyani, Allison R. Dick, Waseem Q. Anani, Melanie S. Sanford
This paper describes a mild palladium-catalyzed method for the regioselective chlorination, bromination, and iodination of arene C−H bonds using N-halosuccinimides as oxidants. These transformations have been applied to a wide array of substrates and can provide products that are complementary to those obtained via conventional electrophilic aromatic substitution reactions.

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