ol060747f_si_002.pdf (3.12 MB)
A Simple Catalytic Method for the Regioselective Halogenation of Arenes
journal contributionposted on 2006-06-08, 00:00 authored by Dipannita Kalyani, Allison R. Dick, Waseem Q. Anani, Melanie S. Sanford
This paper describes a mild palladium-catalyzed method for the regioselective chlorination, bromination, and iodination of arene C−H bonds using N-halosuccinimides as oxidants. These transformations have been applied to a wide array of substrates and can provide products that are complementary to those obtained via conventional electrophilic aromatic substitution reactions.