The variable extracts of six medicinal plants prepared in 80% methanol and distilled water and were tested for their antimycotic activity against five different phytopathogenic fungi such as Alternaria carthami, Alternaria humicola, Fusarium oxysporum, Fusarium roseum, Pullularia pullulans. Among all the plant extracts, methanol extract of Lawsonia inermis and Hyptis sauvolens leaves were showed significant antifungal activity against targeted phytopathogens. Methanol extracts displayed maximum antifungal activity as compared to aqueous extracts. The antifungal activity revealed by these plants could be attributed to the synergetic effect of two or more chemical constituent.