Enantioselective Chromatographic Resolution and One-Pot Synthesis of
Enantiomerically Pure Sulfoxides over a Homochiral Zn−Organic Framework

Nuzhdin, Alexey L.; Dybtsev, Danil N.; Bryliakov, Konstantin P.; Talsi, Evgenii P.; Fedin, Vladimir P.

doi:10.1021/ja076276p.s001

ja076276p_si_001.pdf (52.46 kB)

Enantioselective Chromatographic Resolution and One-Pot Synthesis of Enantiomerically Pure Sulfoxides over a Homochiral Zn−Organic Framework

journal contribution

posted on 2007-10-31, 00:00 authored by Alexey L. Nuzhdin, Danil N. Dybtsev, Konstantin P. Bryliakov, Evgenii P. Talsi, Vladimir P. Fedin

(R)- and (S)- enantiomers of alkyl aryl sulfoxides can be obtained by chromatographic resolution of the racemic mixtures of the sulfoxides on a microporous homochiral Zn-organic polymer or by simultaneous catalytic oxidation of the corresponding sulfides with H₂O₂ and enantioselective chromatographic resolution of the resulting sulfoxides in a one-pot process.