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Total Synthesis of Pseudodehydrothyrsiferol

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journal contribution
posted on 05.02.2009 by Hideaki Hioki, Masatoshi Motosue, Yasuhiko Mizutani, Akira Noda, Tomoaki Shimoda, Miwa Kubo, Kenichi Harada, Yoshiyasu Fukuyama, Mitsuaki Kodama
An enantioselective total synthesis of pseudodehydrothyrsiferol has been accomplished. The synthetic sequence highlights formation of the highly strained tetrahydropyran C-ring by a Mitsunobu-type SN2 reaction with an oxygen nucleophile.

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