ol6b02722_si_001.pdf (4.09 MB)

Palladium-Catalyzed Aerobic Intramolecular Aminoacetoxylation of Alkenes Enabled by Catalytic Nitrate

Download (4.09 MB)
journal contribution
posted on 18.10.2016 by Jiaming Li, Robert H. Grubbs, Brian M. Stoltz
A mild aerobic intramolecular aminoacetoxylation method for the synthesis of pyrrolidine and indoline derivatives was achieved using molecular oxygen as the oxidant. A catalytic NOx species acts as an electron transfer mediator to access a high-valent palladium intermediate as the presumed active oxidant.

History

Exports