Novel Antiinsectan Oxalicine Alkaloids from Two Undescribed Fungicolous Penicillium spp.
journal contributionposted on 12.02.2003 by Yichao Zhang, Chen Li, Dale C. Swenson, James B. Gloer, Donald T. Wicklow, Patrick F. Dowd
Any type of content formally published in an academic journal, usually following a peer-review process.
15-Deoxyoxalicine B (1) and decaturins A (2) and B (3) have been isolated from Penicillium decaturense and Penicillium thiersii, two previously undescribed species obtained as colonists of wood-decay fungi. The structures were determined by 2D NMR experiments and/or single-crystal X-ray diffraction analysis. These compounds are members of a rare structural class, and decaturins A and B feature a new polycyclic ring system. Decaturin B (3) exhibited potent antiinsectan activity against the fall armyworm (Spodoptera frugiperda).