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Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor

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journal contribution
posted on 15.10.2015 by Danilo Russo, Danilo Spasiano, Marianna Vaccaro, Roberto Andreozzi, Gianluca Li-Puma, Nuno Reis, Raffaele Marotta
Benzoylecgonine (BE) is the major metabolite of cocaine and a contaminant of emerging concern often detected in sewage treatment plant (STP) effluents and surface waters. In this study, an innovative microcapillary film (MCF) array photoreactor made of fluoropolymer material was used to determine the direct photolysis quantum yield of benzoylecgonine at 254 nm. The quantum yield of BE was found to be (6.22 ± 0.19) × 10-3 mol ein-1. The proposed methodology was validated by estimating the quantum yield of caffeine (7.48 10-4 ± 0.64) × 10-4 mol ein-1, which was found in agreement with results published in literature. The MCF uses a very small sample volume (in the order of 330μl per meter length of material) and allows extremely rapid photolysis with a short contact time ranging from a fraction of seconds to a few minutes. This new microfluidics approach presented in this study is particularly useful for determining the photochemical behavior of highly priced pharmaceuticals, illicit drugs, metabolites and uncommon or regulated substances.

History

School

  • Aeronautical, Automotive, Chemical and Materials Engineering

Department

  • Chemical Engineering

Published in

Chemical Engineering Journal

Volume

283

Pages

243 - 250

Citation

RUSSO, D. ...et al., 2015. Direct photolysis of benzoylecgonine under UV irradiation at 254nm in a continuous flow microcapillary array photoreactor. Chemical Engineering Journal, 283, pp. 243-250.

Publisher

© Elsevier

Version

AM (Accepted Manuscript)

Publisher statement

This work is made available according to the conditions of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) licence. Full details of this licence are available at: https://creativecommons.org/licenses/by-nc-nd/4.0/

Publication date

2015

Notes

This paper was accepted for publication in the journal Chemical Engineering Journal and the definitive published version is available at: http://dx.doi.org/10.1016/j.cej.2015.07.061

ISSN

1873-3212

Language

en

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