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Additional file 1: of Stochastic modeling of aging cells reveals how damage accumulation, repair, and cell-division asymmetry affect clonal senescence and population fitness

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posted on 15.07.2019 by Ruijie Song, Murat Acar
Figure S1. A-H. Relative representation of the other parameters in the cases where changing the level of inheritance caused a significant (> 5%) fitness difference. Figure S2. A-H. Relative representation of the other parameters in the cases where changing the maximum repair rate caused a significant (> 5%) fitness difference. Figure S3. A-H. Relative representation of the other parameters in the cases where changing the Michaelis constant km for repair caused a significant (> 5%) fitness difference. Figure S4. A-H. Relative representation of the other parameters in the cases where changing the damage accumulation rate caused a significant (> 5%) fitness difference. Table S1. Parameters with fixed mean values. Table S2. Parameters with values selected from a grid of values. (PDF 1035 kb)

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National Institute on Aging (US)

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