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tPA effect on functional outcome.

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posted on 2014-09-03, 03:30 authored by Yuling Meng, Michael Chopp, Yanlu Zhang, Zhongwu Liu, Aaron An, Asim Mahmood, Ye Xiong

tPA significantly lowered the mNSS scores (A) and reduced frequency of foot faults (B) from Day 14 to 35 after TBI compared to the saline group. tPA treatment significantly improved spatial learning performance from Day 33 to 35 after TBI compared with the saline group (C). *p<0.05 vs TBI+Saline. Data represent mean ± SD. n = 8 (rats/group).