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shAMPK knocks down AMPK and inhibits the effects of liraglutide on AMPK and ACC phosphorylation, and monocyte adhesion.

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posted on 2014-05-16, 02:57 authored by Nadia M. Krasner, Yasuo Ido, Neil B. Ruderman, Jose M. Cacicedo

A: AMPK phosphorylation (Thr172) B: ACC phosphorylation (Ser79). C,D: Infection of HAECs with shAMPK inhibited the liraglutide induced decrease in TNFα (10 ng/mL) and LPS (2 µg/mL ) stimulated monocyte adhesion (n = 6). *p<0.05, **p<0.01, ***p<0.001.