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pLenO-RFP-Let-7c inhibits tumor growth in a xenograft mouse model of HCC in vivo.

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posted on 24.04.2015, 04:27 by Xiuming Zhu, Lingjiao Wu, Jian Yao, Han Jiang, Qiangfeng Wang, Zhijian Yang, Fusheng Wu

(A) Effects of pLenO-RFP-let-7c (Lv-let-7c) and pLenO-RFP (Lv-control, negative control) in the xenograft mouse model are shown. Data are shown as the mean ± S.D. The statistical difference was analyzed by the two-sample t test. (B) qRT-PCR assays of mature let-7c expression in tissues of the Lv-let-7c and Lv-control group. (C) Weight of tumors of mice in the Lv-let-7c and Lv-control groups. Data are shown as the mean ± S.D. The statistical difference was analyzed by the two-sample t test. (D) Photographs of tumors are presented. The three smallest tumors in the Lv-let-7c group are indicated by blue arrows.

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