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pGz Increases eNOS Signaling and IL-10 Expression, whereas it Reduces iNOS, TNF-α and IL-6 Expression.

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posted on 25.03.2015, 03:59 by Arkady Uryash, Jorge Bassuk, Paul Kurlansky, Francisco Altamirano, Jose R. Lopez, Jose A. Adams

A. Left ventricular protein content of endothelial derived nitric oxide synthase (eNOS) and phosphorylated eNOS (p-eNOS) as well as inducible nitric oxide synthase (iNOS), for Sham, MI-CONT and MI-pGz with representative immune blots for each group.* p< 0.01 MI-CONT and MI-pGz vs. Sham. †p< 0.01 MI-CONT vs. MI-pGz. B. Left ventricular protein content of the pro-inflammatory cytokines; Interleukin 6 (IL-6) and Tumor necrosis factor alpha (TNF-α) and the anti-inflammatory cytokine; Interleukin 10 (IL-10) in Sham, MI-CONT and MI-pGz. * p< 0.01 MI-CONT and MI-pGz vs. Sham †p< 0.01 MI-CONT vs. MI-pGz. C. Ratio of anti-inflammatory IL-10 to pro-inflammatory TNF-α cytokines. * p< 0.01 MI-CONT and MI-pGz vs. Sham †p< 0.01 MI-CONT vs. MI-pGz.

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