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pGz Increases eNOS Signaling and IL-10 Expression, whereas it Reduces iNOS, TNF-α and IL-6 Expression.

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posted on 25.03.2015, 03:59 authored by Arkady Uryash, Jorge Bassuk, Paul Kurlansky, Francisco Altamirano, Jose R. Lopez, Jose A. Adams

A. Left ventricular protein content of endothelial derived nitric oxide synthase (eNOS) and phosphorylated eNOS (p-eNOS) as well as inducible nitric oxide synthase (iNOS), for Sham, MI-CONT and MI-pGz with representative immune blots for each group.* p< 0.01 MI-CONT and MI-pGz vs. Sham. †p< 0.01 MI-CONT vs. MI-pGz. B. Left ventricular protein content of the pro-inflammatory cytokines; Interleukin 6 (IL-6) and Tumor necrosis factor alpha (TNF-α) and the anti-inflammatory cytokine; Interleukin 10 (IL-10) in Sham, MI-CONT and MI-pGz. * p< 0.01 MI-CONT and MI-pGz vs. Sham †p< 0.01 MI-CONT vs. MI-pGz. C. Ratio of anti-inflammatory IL-10 to pro-inflammatory TNF-α cytokines. * p< 0.01 MI-CONT and MI-pGz vs. Sham †p< 0.01 MI-CONT vs. MI-pGz.

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