miR-miR co-expression network.

This network was built with the 195 DE miRs which have pearson correlation co-efficient greater than 0.9. Here nodes correspond to miRs, and edges between miRs represent significant co-expression relationships. Top 18 co-expressed hub miRs were represented as square nodes, of which 4 hub miRs belonged to Group 1. The remaining 14 co-expressed hub miRs were novel miRs which were not previously reported to be associated with PD. This network was constructed in Cytoscape interface [26].