SLC4A11 expression is regulated by DNA amplification and methylation in ovarian cancer.
A. Heat map of SLC4A11 copy number changes in TCGA-OV. -1: deletion; 0: no change; 1: amplification; 2: high-amplification. B-D. Heat map (B) and box plots (C-D) of SLC4A11 expression and DNA methylation in TCGA-OV. Patients were divided into high and low methylation groups according to the median value of the two probes (cg11004890 and cg08284598) respectively.