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In vivo tumor characteristics of chemosensitivity on cells xenograft by oxaliplatin.

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posted on 2016-09-26, 17:38 authored by Wen-Shih Huang, Meng-Chiao Hsieh, Cheng-Yi Huang, Yi-Hung Kuo, Shui-Yi Tung, Chien-Heng Shen, Yung-Yu Hsieh, Chih-Chuan Teng, Kam-Fai Lee, Te-Chuan Chen, Ko-Chao Lee, Hsing-Chun Kuo

HCT-116 and HCT-116/OxR cells removed and the section were stained by immunohistochemical analysis as described in text. Immunohistochemical analysis of tumors was conducted, and multiple tumor fields were evaluated per group. Representative images for all groups from both experiments are presented. TUNEL staining revealed significantly greater apoptosis in tumors. H&E staining revealed similar s.c. tumor morphology among all groups of tumors. CD133 and P-gp staining showed expressed tumor cells treated with oxaliplatin.