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In vivo tracing of TRAIL-MSCs.

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posted on 12.09.2016, 17:36 authored by Zhen Zhang, Ming Li, Feixue Chen, Lixiang Li, Jun Liu, Zhen Li, Rui Ji, Xiuli Zuo, Yanqing Li

(A) The expression of TRAIL on the surface of tumors from mice treated with TRAIL-MSCs (S-TRAIL-MSCs), the inside of tumors from mice treated with TRAIL-MSCs (I-TRAIL-MSCs), the surface of tumors from mice treated with nontransduced MSCs (S-MSCs) and the inside of tumors from mice treated with nontransduced MSCs (I-MSCs) were evaluated by qPCR. *** P<0.001, n = 5. The data are presented as the mean ± SD. (B) Endomicroscopy images of TRAIL-MSC compared with nontransduced MSC and PBS groups localized to the surface and inside of tumors. Scale bar = 50 μm. (C) The mean gray-scale value of ROIs of from TRAIL-MSC, MSC and PBS groups on the surface and inside of tumors. * P<0.05, n = 5. The data are presented as the mean ± SD.

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