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elt-2 regulated genes.

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posted on 27.05.2015, 03:44 by Dena H. S. Block, Kwame Twumasi-Boateng, Hae Sung Kang, Jolie A. Carlisle, Alexandru Hanganu, Ty Yu-Jen Lai, Michael Shapira

A. microarray analysis. Gene expression profiles for 426 transcripts differentially expressed between elt-2(RNAi) and control-treated wildtype worms, when exposed to P. aeruginosa (PA, 12 hours), compared to E. coli (EC). Left, heatmap of raw values (log2(fold change over reference RNA)), with bars highlighting clusters of interest; right, curves depicting median-centered expression profiles; black curves represent the median. B. GATA motif distribution. Measured for the consensus TGATAA in 1000bp upstream sequences of genes of the designated subsets; shown as #motifs/gene/100bp; asterisks mark significant deviations from random distribution (p<10–8, χ2).