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<b>Myeloma - Myeloma</b> | Interpretable prognosis for susceptibility to active anti-cancer molecular forms, based on amides/carboxylic acids - hydrolysis derivatives of natural nitrile glycosides, of transcriptome cell lines inherent in tumors

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posted on 2024-10-11, 17:38 authored by Vasil TsanovVasil Tsanov
<p dir="ltr">excerpt from an edition:</p><p dir="ltr"><b>A T L A S</b> - Interpretable prognosis for susceptibility to active anti-cancer molecular forms, based on amides/carboxylic acids - hydrolysis derivatives of natural nitrile glycosides, of transcriptome cell lines inherent in tumors /Second supplemented edition/ - DOI: <a href="http://doi.org/10.5281/zenodo.13777292" target="_blank">10.5281/zenodo.13777292</a> | ISBN: 978-619-91534-6-8</p><p>--------------</p><p dir="ltr">From the data on the interpretable prognosis of sensitivity to active anti-cancer molecular forms (<i>p.10 </i>form the ATLAS) of transcriptome cell lines inherent in tumors in the <b><i>Myeloma </i></b>(<b><i>a.</i></b> & <b><i>b.</i></b>), it is concluded that:</p><p dir="ltr"><b>- some of the main potential medicines:</b></p><p dir="ltr"><i>2-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)propanamide</i> and <i>.../propanoic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>2-hydroxy-2-methylpropanamide</i> and <i>.../propanoic acid</i> ,</p><p dir="ltr"><i>(R)-2-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butanamide</i> and <i>.../butanoic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>(R)-2-hydroxy-2-methylbutanamide</i> and<i> .../butanoic acid</i> ,</p><p dir="ltr"><i>(S)-4-amino-2-methylene-4-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl sulfate</i> and <i>2-((S)-carboxy(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)allyl sulfate</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>(S)-4-amino-3-hydroxy-2-methylene-4-oxobutyl sulfate</i> and<i> (S)-2-(carboxy(hydroxy)methyl)allyl sulfate</i> ,</p><p dir="ltr"><i>(2S,3R)-2-hydroxy-4-methoxy-1-methyl-6-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,2,3,6-tetrahydropyridine-3-carboxamide</i> and <i>.../carboxylic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>(2S,3R)-2,3-dihydroxy-4-methoxy-1-methyl-6-oxo-1,2,3,6-tetrahydropyridine-3-carboxamide</i> and <i>.../carboxylic acid </i>,</p><p dir="ltr"><i>(Z)-2-carbamoyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-2-en-1-yl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate</i> and <i>(Z)-2-((((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)oxy)methyl)-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-2-enoic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>(Z)-2-carbamoyl-4-hydroxybut-2-en-1-yl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate</i> and <i>(Z)-4-hydroxy-2-((((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)oxy)methyl)but-2-enoic acid</i> ,</p><p dir="ltr">the rest ACCF can be found in the file and the ATLAS ;</p><p dir="ltr"><b>- certain medicines for duplication of treatment and/or replacement for medical reasons:</b></p><p dir="ltr"><i>2-(4-(((2S,3R,4S,5S,6R)-6-((((2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)phenyl)acetamide</i> and<i> .../acetic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>2-(4-hydroxyphenyl)acetamide</i> and <i>.../acetic acid</i> ,</p><p dir="ltr"><i>(S)-3-(hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-3-enamide</i> and <i>.../enoic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>(S)-2-hydroxy-3-(hydroxymethyl)but-3-enamide</i> and <i>.../enoic acid</i> ,</p><p dir="ltr"><i>(S)-4-amino-2-methylene-4-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl 4-hydroxybenzoate</i> and <i>(S)-3-(((4-hydroxybenzoyl)oxy)methyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-3-enoic acid</i> in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell <i>(S)-4-amino-3-hydroxy-2-methylene-4-oxobutyl 4-hydroxybenzoate</i> and <i>(S)-2-hydroxy-3-(((4-hydroxybenzoyl)oxy)methyl)but-3-enoic acid</i> ,</p><p dir="ltr">the rest ACCF can be found in the file and the ATLAS.</p><p>-------</p><p dir="ltr"><b><u>Important! Do not forget to comply with the current clinical control.</u></b></p><p dir="ltr">The idea timeline: <a href="https://anti-cancer.eu/" target="_blank">anti-cancer.eu</a></p><p><br></p>

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