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Myeloma - Myeloma | Interpretable prognosis for susceptibility to active anti-cancer molecular forms, based on amides/carboxylic acids - hydrolysis derivatives of natural nitrile glycosides, of transcriptome cell lines inherent in tumors

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posted on 2024-10-11, 17:38 authored by Vasil TsanovVasil Tsanov

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A T L A S - Interpretable prognosis for susceptibility to active anti-cancer molecular forms, based on amides/carboxylic acids - hydrolysis derivatives of natural nitrile glycosides, of transcriptome cell lines inherent in tumors /Second supplemented edition/ - DOI: 10.5281/zenodo.13777292 | ISBN: 978-619-91534-6-8

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From the data on the interpretable prognosis of sensitivity to active anti-cancer molecular forms (p.10 form the ATLAS) of transcriptome cell lines inherent in tumors in the Myeloma (a. & b.), it is concluded that:

- some of the main potential medicines:

2-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)propanamide and .../propanoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell 2-hydroxy-2-methylpropanamide and .../propanoic acid ,

(R)-2-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butanamide and .../butanoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (R)-2-hydroxy-2-methylbutanamide and .../butanoic acid ,

(S)-4-amino-2-methylene-4-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl sulfate and 2-((S)-carboxy(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)allyl sulfate in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (S)-4-amino-3-hydroxy-2-methylene-4-oxobutyl sulfate and (S)-2-(carboxy(hydroxy)methyl)allyl sulfate ,

(2S,3R)-2-hydroxy-4-methoxy-1-methyl-6-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,2,3,6-tetrahydropyridine-3-carboxamide and .../carboxylic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (2S,3R)-2,3-dihydroxy-4-methoxy-1-methyl-6-oxo-1,2,3,6-tetrahydropyridine-3-carboxamide and .../carboxylic acid ,

(Z)-2-carbamoyl-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-2-en-1-yl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate and (Z)-2-((((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)oxy)methyl)-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-2-enoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (Z)-2-carbamoyl-4-hydroxybut-2-en-1-yl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate and (Z)-4-hydroxy-2-((((E)-3-(4-hydroxy-3-methoxyphenyl)acryloyl)oxy)methyl)but-2-enoic acid ,

the rest ACCF can be found in the file and the ATLAS ;

- certain medicines for duplication of treatment and/or replacement for medical reasons:

2-(4-(((2S,3R,4S,5S,6R)-6-((((2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)tetrahydrofuran-2-yl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)phenyl)acetamide and .../acetic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell 2-(4-hydroxyphenyl)acetamide and .../acetic acid ,

(S)-3-(hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-3-enamide and .../enoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (S)-2-hydroxy-3-(hydroxymethyl)but-3-enamide and .../enoic acid ,

(S)-4-amino-2-methylene-4-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl 4-hydroxybenzoate and (S)-3-(((4-hydroxybenzoyl)oxy)methyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-3-enoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (S)-4-amino-3-hydroxy-2-methylene-4-oxobutyl 4-hydroxybenzoate and (S)-2-hydroxy-3-(((4-hydroxybenzoyl)oxy)methyl)but-3-enoic acid ,

the rest ACCF can be found in the file and the ATLAS.

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Important! Do not forget to comply with the current clinical control.

The idea timeline: anti-cancer.eu


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