Biliary tract - Ductus biliaris | Interpretable prognosis for susceptibility to active anti-cancer molecular forms, based on amides/carboxylic acids - hydrolysis derivatives of natural nitrile glycosides, of transcriptome cell lines inherent in tumors
excerpt from an edition:
A T L A S - Interpretable prognosis for susceptibility to active anti-cancer molecular forms, based on amides/carboxylic acids - hydrolysis derivatives of natural nitrile glycosides, of transcriptome cell lines inherent in tumors /Second supplemented edition/ - DOI: 10.5281/zenodo.13777292 | ISBN: 978-619-91534-6-8
--------------
From the data on the interpretable prognosis of sensitivity to active anti-cancer molecular forms (p.10 form the ATLAS) of transcriptome cell lines inherent in tumors in the Biliary tract (a. & b.), it is concluded that:
- some of the main potential medicines:
(R)-3-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butanamide and .../butanoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (R)-2-hydroxy-3-methylbutanamide and .../butanoic acid ,
(R)-3-methyl-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)but-3-enamide and .../enoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (R)-2-hydroxy-3-methylbut-3-enamide and .../enoic acid ,
(Z)-2-((2S,3R,4S,6R)-2,3-dihydroxy-4-methoxy-6-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)cyclohexylidene)acetamide and .../acetic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (E)-2-((2S,3R,4S,6R)-2,3,6-trihydroxy-4-methoxycyclohexylidene)acetamide and .../acetic acid ,
((2R,3S,4S,5R,6R)-6-(((2R,3S)-4-amino-3-methyl-4-oxobutan-2-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)methyl (2S,3R)-2-ethyl-2,3-dihydroxybutanoate and (2S,3R)-3-(((2R,3R,4S,5S,6R)-6-((((2S,3R)-2-ethyl-2,3-dihydroxybutanoyl)oxy)methyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)-2-methylbutanoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (2S,3R)-3-hydroxy-2-methylbutanamide and .../butanoic acid ,
(1S,4R)-4-carbamoyl-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)cyclopent-2-en-1-yl sulfate and (1S,4R)-4-carboxy-4-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)cyclopent-2-en-1-yl sulfate in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (1R,4R)-4-carbamoyl-4-hydroxycyclopent-2-en-1-yl sulfate and (1R,4R)-4-carboxy-4-hydroxycyclopent-2-en-1-yl sulfate ,
the rest ACCF can be found in the file and the ATLAS ;
- certain medicines for duplication of treatment and/or replacement for medical reasons:
(R)-2-(hydroxymethyl)-2-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butanamide and .../butanoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (R)-2-hydroxy-2-(hydroxymethyl)butanamide and .../butanoic acid ,
(Z)-4-(((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)but-2-enamide and .../enoic acid in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (Z)-4-hydroxybut-2-enamide and .../enoic acid ,
(S)-4-amino-2-methylene-4-oxo-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)butyl sulfate and 2-((S)-carboxy(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)methyl)allyl sulfate in stoichiometric ratio by mass 4.87:1 is released inside the cancer cell (S)-4-amino-3-hydroxy-2-methylene-4-oxobutyl sulfate and (S)-2-(carboxy(hydroxy)methyl)allyl sulfate ,
the rest ACCF can be found in the file and the ATLAS.
-------
Important! Do not forget to comply with the current clinical control.
History
Usage metrics
Categories
- Cell development, proliferation and death
- Cell metabolism
- Biochemistry and cell biology not elsewhere classified
- Genomics and transcriptomics
- Bioinformatics and computational biology not elsewhere classified
- Translational and applied bioinformatics
- Biological network analysis
- Molecular evolution
- Other biological sciences not elsewhere classified
- Medical biochemistry - carbohydrates
- Medical biochemistry and metabolomics not elsewhere classified
- Cancer cell biology
- Cancer therapy (excl. chemotherapy and radiation therapy)
- Oncology and carcinogenesis not elsewhere classified
- Haematological tumours
- Solid tumours
- Paediatrics not elsewhere classified
- Other biomedical and clinical sciences not elsewhere classified
- Natural products and bioactive compounds
- Organic chemistry not elsewhere classified
- Biologically active molecules
- Cheminformatics and quantitative structure-activity relationships
- Molecular medicine
- Medicinal and biomolecular chemistry not elsewhere classified
- Other chemical sciences not elsewhere classified