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(a) VIP and (b) coefficients for the PLS model.

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posted on 2017-06-29, 18:08 authored by Liangshan Ming, Zhe Li, Fei Wu, Ruofei Du, Yi Feng

(a) VIP and (b) coefficients for the PLS model.

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A two-step approach for fluidized bed granulation in pharmaceutical processing: Assessing different models for design and control
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binder solution rate X 3factormoisture content Y 3flowability Y 1approachtemperature Y 2quality attributesPBDresponse surface modelbinder-to-powder ratio X 5granuleinlet air temperature X 1MLP modelscompactability Y 5granulesBBDscanning electron microscopePLSfluidized bed granulationparameteraggregation index Y 4RSManalysis

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