Without degradation, angiogenesis is inhibited at (Figure 3F).
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
(A) shows that tip cell matrix degradation promotes sprout development at by carving out a path for migration, called a vascular guidance tunnel (B). (C) depicts sprout formation and branching with ECM degradation at , a density not typically conducive to branching, suggesting that high matrix heterogeneity (D) created by tip cell degradation may be a mechanism for branching (Video S3). (E) VEGF gradient profile (pg) shows strong gradient along leading edges of sprout. Snapshots at 14 hours.