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Wearing of articular cartilage of the knee joint in PXR knockout mouse.

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posted on 2015-03-06, 10:19 authored by Kotaro Azuma, Stephanie C. Casey, Tomohiko Urano, Kuniko Horie-Inoue, Yasuyoshi Ouchi, Bruce Blumberg, Satoshi Inoue

Representative microscopic image of articular cartilage of 8-month-old and 13-month-old wild-type and PXR knockout mice are shown. Arrowheads indicate lateral articular cartilage of the tibia.

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Pregnane X Receptor Knockout Mice Display Aging-Dependent Wearing of Articular Cartilage
PLOS ONEPLOS ONE

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PXR knockout micetibial articular cartilagesequence similarity 20SXRchondrocyteFam 20a expressiongeneArticular Cartilage Steroidarticular cartilagevitamin K 2.pregnane X receptor

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