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Vernodalin induces cell cycle arrest at G0/G1 stage.

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posted on 20.02.2013, 02:02 by Chung Yeng Looi, Aditya Arya, Foo Kit Cheah, Bushra Muharram, Kok Hoong Leong, Khalit Mohamad, Won Fen Wong, Nitika Rai, Mohd Rais Mustafa

MCF-7 and MDA-MB-231 cells were treated with indicated dosages of verdonalin for 24 hours. Cells were ethanol-permeabilized and stained with propidium iodide before subjected to flow cytometry analysis. Representative figures of cell cyle distribution (G0/G1, S, and G2/M) showing accumulation of vernodalin-treated cells in G0–G1 stage. Data were mean ± SD of two independent experiments.