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Upregulation of microglial marker CD68 in the thalamus and cerebral cortex of Cln6nclf mice.

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posted on 01.11.2013, 03:14 authored by Jeremy P. Morgan, Helen Magee, Andrew Wong, Tarah Nelson, Bettina Koch, Jonathan D. Cooper, Jill M. Weimer

Quantitative thresholding analysis in Cln6nclf mice was compared to age matched WT, revealing a significant increase in the expression of the microglia marker CD68 in the VPM/VPL (A), M1 (C), S1BF (B), and V1 (D) regions in the Cln6nclf mouse over WT. [Mean% immunoreactivity +/− SEM, n = 3 (*p≤0.05, **p≤0.01, ***p≤0.001, ****p≤0.0001)].