Two possible scenarios of cooperative effect in YhdE catalyzed dTTP hydrolysis.

figure

posted on 2015-08-07, 03:53 authored by Nan Wang, Jiahong Jiang, Xichen Li, Hongwei Tan, Jimin Zheng, Guangju Chen, Zongchao Jia

<p>Orange arrow indicates that dTTP binds YhdE first and green arrow indicates that YhdE dimer forms first.</p>

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DOI - Is supplement to Molecular Dynamics Simulation Studies of dTTP Binding and Catalysis Mediated by YhdE Dimerization

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Biological Sciences

Keywords

Free Energy Calculations YhdE dimerization allosteric communication network Molecular Dynamics Simulation Studies cell metabolism pathway dTTP binding sites YhdE Dimerization YhdE dTTP binding

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