Transport of bile acids in everted gut sacs.
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(A) Amount of TCA accumulated in the serosal fluid after a 30 min incubation of gut sacs from the proximal one-third and distal one-third portions of the small intestine of male Fabp6+/+ (n = 4), female Fabp6+/+ (n = 3–4) mice (black bars), male Fabp6−/− (n = 4) and female Fabp6−/− (n = 5) mice (white bars). (B) Amount of TCA accumulated in the gut sac tissue at the end of the assay incubation period. *P<0.025, **P<0.01, vs. wild-type of the same sex.