Figure_4.tif (1.58 MB)

Translocation of GFP-tagged RasGRP1 in living cells after treatment with PMA or I3A.

Download (0 kB)
posted on 2013-08-21, 01:37 authored by Xiaohua Song, Ana Lopez-Campistrous, Lucy Sun, Nancy A. Dower, Noemi Kedei, Jing Yang, Jessica S. Kelsey, Nancy E. Lewin, Tim E. Esch, Peter M. Blumberg, James C. Stone

Cells expressing GFP-RasGRP1 were treated with 1000 nM PMA or I3A. The translocation pattern was examined in live cells as a function of time. The results of duplicate experiments with I3A are shown. The images shown are representative of four independent experiments. The scale bar represents 10 µm.