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Top panel: optic nerves in cross-section and stained by p-Phenylenediamine for control and LHON patient (25x magnification).

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posted on 19.02.2013, 19:39 by Giovanni Rizzo, Kevin R. Tozer, Caterina Tonon, David Manners, Claudia Testa, Emil Malucelli, Maria Lucia Valentino, Chiara La Morgia, Piero Barboni, Ruvdeep S. Randhawa, Fred N. Ross-Cisneros, Alfredo A. Sadun, Valerio Carelli, Raffaele Lodi

In the LHON patient only a small patch of fibers remains (arrow) in the super-nasal quadrant. Bottom panel: lateral geniculate nuclei (LGN) of control and LHON patients with all magnocellular (1 and 2) and parvocellular (3–6) layers identified (25x magnification). Insets represent samples of each zone at 200x magnification.