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The xylose reductase and xylitol dehydrogenase genes from S. cerevisiae complement C. albicans deletion mutants of the equivalent genes.

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posted on 13.11.2013 by Doreen Harcus, Daniel Dignard, Guylaine Lépine, Chris Askew, Martine Raymond, Malcolm Whiteway, Cunle Wu

(A) S. cerevisiae GRE3 (CA255), and (B) S. cerevisiae SOR1 (CDH139) complement the C. albicans gre3 and xyl2 deletion mutants respectively. Strains were grown aerobically at 30°C in 2% xylose (SX) or 2% xylitol (ST). The optical density was measured over a period of 14 days, n=3.

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