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The xylose isomerase gene XYLA from Piromycessp. complements a double gre3/xyl2 deletion or single gre3 deletion in C. albicans.

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posted on 13.11.2013 by Doreen Harcus, Daniel Dignard, Guylaine Lépine, Chris Askew, Martine Raymond, Malcolm Whiteway, Cunle Wu

Growth analysis in synthetic medium (SC) with 2% xylose as the sole carbon source for C. albicans strains: gre3-9 (gre3 deletion), gre3/xyl2-3 (gre3 xyl2 double deletion), CDH128 (gre3/xyl2-3 with the integrated Pir.XYLA) and CDH140 (gre3-9 with the integrated Pir. XYLA). The optical density was measured over a period of 6 days, n=3.

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