The percentages of circulating Th17 and Th1 cells in patients after treatment.
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PA means patient. (A and B) The percentages of circulating Th17 and Th1 cells before and after chemotherapy in B-NHL. (C and D) Circulating Th17 cells were significantly increased in treated B-NHL patients compared to those before treatment (P = 0.0098) while Th1 cells dramatically reduced (P = 0.0137). (E and F) Both Th17 and Th1 cells returned to normal values after treatment in B-NHL. (G) Circulating Th17 cells were dramatically elevated in relapsed patients (RL B-NHL) compared with new diagnosed patients (New B-NHL) (P<0.0001) and even normal individuals (NC) (P = 0.0015). (H) Circulating Th1 cells in relapsed patients were similar to new diagnosed patients (P = 0.7444) but still higher than normal individuals (P = 0.0014).). * P<0.05; ** P<0.01; *** P<0.001; ns, non-significant