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The p53-Mdm2-MdmX network displayed as a heuristic Molecular Interaction Map (MIM) [25]–[27].

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posted on 05.02.2010, 01:21 authored by Sohyoung Kim, Mirit I. Aladjem, Geoffrey B. McFadden, Kurt W. Kohn

Four pathways of p53 regulation are highlighted in the following panels: A) p53 transactivation, B) p53 degradation, C) Mdm2 degradation, D) MdmX degradation.