The malignant degree of teratocarcinoma increased after sequential transplantation.

A. Different generation of teratocarcinoma stem cells and ES cells were injected subcutaneously into nude mice on both sides of the body; the teratocarcinoma growth of G3 cells was significantly faster than that of ES cells. B. With the increasing of transplantation generation, it accelerated the tumor formation of teratocarcinoma stem cells.