The major structural features of E. modestus KIFC1.
(A) This figure shows the three structural domains of KIFC1. The C-terminus (346–700 aa) contains the conserved head (yellow bar) that “walks” along the microtubules. The stalk region (154–346 aa) forms an extended coiled-coil region (pink bar). The N-terminus (1–154 aa) contains the divergent tail (blue bar) that carries different cargoes. (B) This figure shows the putative 3-D structure of KIFC1. The head, stalk, and tail are labelled by different colors. See the website http://zhanglab.ccmb.med.umich.edu/I-TASSER/output/S123537/ for more details.