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Download fileThe levels of LDH, CK, IL-6, TNF-α, ROS, MDA and SOD.
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posted on 2014-10-14, 03:00 authored by Mingming Zhang, Xiaolin Niu, Jianqiang Hu, Yuan Yuan, Shuhong Sun, Jiaxing Wang, Wenjun Yu, Chen Wang, Dongdong Sun, Haichang WangThe LDH, CK, IL-6 and TNF-α levels(A–D); Representative images of DHE staining(E); Quantification of DHE staining(F); MDA and SOD levels(G, H). The columns and error bars represent means and SD. Data were obtained from at least three independent experiments.*P<0.05 vs. H/R, #P<0.05 vs. H/R+Lin28a.
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Lin 28a overexpressionLin 28a cDNA transfectionhgldhrosigfmitochondrial biogenesisLin 28a knockdownLin 28a Protects1rATP productionCardiomyocytes biomarkers releaseckLin 28a siRNA transfectioncardiomyocyte apoptotic indexLin 28a siRNAmitochondria biogenesisPI 3K inhibitor wortmanninintracellular reactive oxygen speciesLIN 28AAlleviating Mitochondrial DysfunctionLin 28acDNA 72 hblot analysis.ResultsOur results