# The hTLR stimulatory score distributions for segment 6.

10,994 IAVs, including 3,324 avian (red), 6,658 human (green) and 1,012 mammalian (blue) IAVs were used in this analysis. (A) The distributions of the hTLR stimulatory scores of segment 6 genomic RNAs. The x-axis represents Score S, the y-axis represents Score N. (B) The relative frequency distribution of Score S from segment 6 genomic RNAs. The x-axis indicates Score S, the y-axis gives the relative frequency. (C) The relative frequency distribution of Score N from segment 6 genomic RNAs. The x-axis represents Score N, the y-axis represents the relative frequency. (D) The distribution of the hTLR stimulatory scores of segment 6 genomic RNAs from 6,658 human IAVs (gray). The pandemic-associated IAVs are highlighted. The x-axis represents Score S, and the y-axis represents Score N.