The effect of TGFβ-inhibitors in fPCLS on viability, gene expression of fibrosis markers and collagen 1 protein expression.
Figures are generally photos, graphs and static images that would be represented in traditional pdf publications.
The effect of TGFβ-inhibitors perindopril (n = 5), valproic acid (n = 4), rosmarinic acid (n = 4), tetrandrine (n = 4) and pirfenidone (n = 5) on the viability (A), on the gene expression of fibrosis markers Hsp47, αSma and Pcol1A1 (B) and on the collagen 1 protein expression (pictures are from a representative experiment) (C) of fPCLS from livers from BDL rats incubated for 48 hours. Error bars represent SEM. Significant decrease: *p<0.05 vs 48h, #p<0.05 vs 0 hours, +p<0.05 vs 24 hours.