The dynamic effect of active or passive scratching an itch were analyzed in direct contrast to the itch condition.
Actively scratching an itch (blue) deactivated the ACC, the ventromedial prefrontal Cortex, midbrain (VTA), while the effect of passive scratching was found only in the ACC (green). Standard Talairach space coordinates (x, y, z). The color tones displayed correspond to Z score values as depicted in the color bars (at the same scale). R = Right; L = Left.